Prof. Isabella A. Quakyi
Professor
Education and Qualification
Education: University of London, School of Hygiene and Tropical. Medicine, London, England University of London, England Brunel University, Uxbridge, Middlesex, England. London School of Hygiene and Tropical Medicine, London University of London, London, England University of Surrey, Guildford, Surrey, England | Qualification: PhD MSc Certificate, Tropical Medicine and Hygiene
B.Sc. (Hons.) |
Working Experience
Emerita Professor Dept. of Biological Environmental and Occupational Health Sciences, School of Public Health, College of Health Sciences, University of Ghana, Legon. April, 2019.
Professor of Immunology and Parasitology: School of Public Health, The College of Health Sciences, University of Ghana, Legon, Accra, Ghana. Nov. 2001 to present.
Dean: School of Public Health, College of Health Sciences, University of Ghana, Legon, Accra. 2006 Aug. to Jul. 2007
Director: School of Public Health, College of Health Sciences, University of Ghana, Legon, Accra. 2002 Oct. to Jul. 2006
Acting Head of Dept.: Biological Environmental and Occupational Health Sciences, 2002 Oct. to Jul. 2006
Adjunct Professor: Georgetown University, Departments of Biology,
Microbiology & Immunology. 2001 Nov. to Present
Associate Research Professor: Georgetown University, Departments of Biology,
Microbiology & Immunology. 1990 to Oct. 2001
Visiting Professor: Faculty of Medicine and Biomedical Sciences, University of
Yaounde I, Yaounde, Cameroon. 1994 – 2001
Visiting Scientist: International Institute for Research and scientific Development in Africa (IIRSDA), Adiopodome, Abidjan, Cote d’Ivore, 1993 – 1994.
Guest Researcher: National Institutes of Health, NIAID/LPD. 1990 Aug. to 2001
Scientist: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Laboratory of Parasitic Disease, Malaria Section 1983 Jun. to Jul. 1990; Also affiliated with the New York University Medical Center, Department of Parasitology, NYU, New York from 1983 Jun. to Aug. 1985
Head, Immunology Unit: Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana 1981‑1983
Lecturer in Immunology: Department of Haematology, University of Ghana Medical School, Accra, Ghana1980‑1983
Principal Research Assistant: Immunology Unit, Department of Microbiology, University of Ghana Medical School, Accra, Ghana. Carried out research to establish baseline immunological parameters and study of humoral immune responses to parasitic diseases in health and disease. 1974‑1977
Visiting Scientist at the following institutions: Nuffield Laboratories of Comparative Medicine, Regent's Park, London, England; Department of Chemical Pathology, The Westminister Teaching Hospital, University of London, The Bone and Joint Research Unit, The London Medical College, University of London; The Wellcome Research Laboratories, Beckenham, Kent, England. Carried out research into the seroepidemiology and immunopathological sequelae of malaria. 1977‑1980
Commonwealth Tropical Medicine Studentship Award for Practical Training in Immunology and Parasitology at the following laboratories:
London School of Hygiene and Tropical Medicine, London, England; Nuffield Laboratories of Comparative Medicine, Regent's Park, London, England; Mckindoe Research Institute, Sussex, England; Wellcome Research Laboratories, Beckenham, Kent, England; Mckindoe Research Institute, East Grinstead, Sussex, England; Wellcome Research Laboratories, Beckenham, Kent, England; The London Hospital Medical College, Department of Clinical Immunology, Whitechapel, England. The training programme included: research and manufacture of immunological reagents; preparation of parasitic antigens and antibodies; development and evaluation of immunodiagnostic techniques for use in parasitic, connective tissue, and autoimmune disease. 1973‑1974
University of Surrey, Guildford, Surrey, England. Worked on the carriage of Staphyloccus aureus and effect of carriage on secretory immunoglobulin A in humans. 1970‑1973
Research Assistant: National Institute of Health and Medical Research, Korle‑Bu, Accra, Ghana: Involved in research on Kwashiorkor and protein calorie malnutrition. 1965-1966
Publications
BOOKS AND BOOK CHAPTERS
Good, M. F., Weiss, W., Pombo, D., Maloy, L. W., Quakyi, I. A., Lunde, M. M., Riley, E. M., Menon, A., Alling, D. W., de la Cruz, V. F., Houghten, R. A., Berzofsky, J. A. and Miller, L. H.: (1988) T cell epitopes of the malaria circumsporozoite protein map to polymorphic segments of the molecules. In Vaccines 88. New Chemical and Genetic Approaches to Vaccination. Prevention of AIDS and other viral, bacterial, and parasitic diseases, (eds. H. Ginsberg, F. Brown, R. A. Lerner, and R. M. Chanock). Cold Spring Harbour Laboratory, New York, pp. 67‑70.
Kumar, S., Miller, L. H., Quakyi, I. A., Keister, D. B., Maloy, W. L., Moss, B. and Good, M. F.: (1989) The cytotoxic T‑cell response to Plasmodium falciparum circumsporozoite protein is genetically restricted and maps to the variant region of the protein. In Vaccines 89. Modern approaches to new vaccines including prevention of AIDS. (eds. R. A. Lerner, H. Ginsberg, R. M. Chanock, and F. Brown). Cold Spring Harbour Laboratory, New York, pp. 305‑310.
Kaslow, D. C., Good, M. F., Syin, C., Quakyi, I. A., Keister, D. B. and Miller, L. H.: (1989) Molecular analysis of zygote/ookinete target antigen of transmission‑blocking immunity in humans and avian malarias. In Vaccines 89. Modern approaches to new vaccines including prevention of AIDS, (eds. R. A. Lerner, H. Ginsberg, R. M. Chanock, and F. Brown). Cold Spring Harbour Laboratory, New York, pp. 319‑324.
Carter, R., Kumar, N., Quakyi, I. A., Good, M., Mendis, K., Graves, P. and Miller, L. H.: (1988) Immunity to sexual stages of malaria parasites. In Progress in Allergy, special edition. Malaria Immunology, (eds. P. Perlmann and H. Wigzell) 41:193‑214
Quakyi I.A., Ahlers J.D., 1999. CD4+ T helper cell responses-Lymphoproliferation. Part VII Immunological Techniques. In Malaria methods and protocols, Methods in Molecular Medicine. D.L Doolan. Humana Press, Totowa, NJ.
JOURNAL ARTICLES
Anteson, R. K., Sekimoto, S., Funkawa, S. and Quakyi, I. A.: (1978) Studies on toxoplasma antibodies in a group of pregnant women and their neonates. Ghana Med. J. 17(4):203.
Quakyi, I. A., Voller, A., Hall, A. P., Johnson, G. D., Holborow, E. J. and Moody, A. H.: (1979) Immunological abnormalities in caucasians with malaria. Immunology (ltrs) 1:153.
Quakyi, I. A.: (1980). The development and validation of an enzyme‑linked immunosorbent assay for malaria. Trop. Med. Para. 42:325‑333.
Riches, P. G., Quakyi, I. A., Gibbs, H. R. and Addison, A. E.: (1980) Normal serum immunoglobulin and albumin levels in adult Ghanians compared with levels in adults in Europe. Trop. Geor. Med. 32:151‑157.
Guerra‑Caceres, J. G., Bryceson, A. D. M., Quakyi, I. A. and Spry, C. F. F.: (1980) Studies of the mechanisms of adverse reactions produced by diethylcarbamazine in patients with onchocerciasis ‑ Mazzotti reaction. Parasite Immunol. 3:121‑131.
Adu, D., Gwyn‑Williams, D., Quakyi, I. A., Voller, A., Anim‑Addo, T., Bruce‑Tagoe, A. A., Johnson, G. D. and Holborow, E. J.: (1982) Anti‑ssDNA and antinuclear antibodies in human malaria. Clin. Exp. Immunol. 49:310‑316.
McCutchan, T. F., Mullins, J. A., Dame, J. B., Quakyi, I. A., Graves, P. M., Rake, I. C. and Allegra, C. J.: (1984) A mechanism of pyrimethamine resistance in recent isolates of P. falciparum. Antimicrob. Agents Chemother. 26:656‑659.
Enea, V., Ellis, J., Zavala, F., Arnot, D. E., Asavanichi, A., Masuda, A., Quakyi, I. and Nussenzweig, R.: (1984) DNA cloning of Plasmodium falciparum circumsporozoite gene: amino acid sequence of repetitive epitope. Science 225:628‑630.
Zavala, F., Tam, J., Hollingdale, M., Cochrane, A., Quakyi, I. A., Nussenzweig, R. and Nussenzweig, V.: (1985) Rationale for development of a synthetic vaccine against Plasmodium falciparum malaria. Science 228:1436‑1440.
Chulay, J. D., Schneider, I., Cosgriff, T. M. Hoffman, S. L., Ballou, W. R., Quakyi, I. A., Carter, R., Trosper, J. H. and Hockmeyer, W. T.: (1986) Malaria transmitted to humans by mosquitoes infected from cultured Plasmodium falciparum. Am. J. Trop. Med. Hyg. 35:66‑68.
Sherwood, J. A., Spitalnik, S. L. Alex, S. B., Quakyi, I. A. and Howard, R. J.: (1986) Plasmodium falciparum and P. knowlesi: initial identification and characterization of malaria synthesized glycolipids. Exp. Parasit. 62:127‑141.
Mucenski, C. M., Guerry, P., Buesing, M., Szarfman, A., Trosper, J., Walliker, D., Watt, G., Sangalang, R., Ranoa, C. P., Tuazon, M., Majam, O. R., Quakyi, I. A., Scheibel, W., Coross, J., Olaon, J. and Perine, P. L.: (1986) Evaluation of a synthetic oligonucleotide probe for diagnosis of Plasmodium falciparum infections. Am. J. Trop. Med. Hyg. 35:912‑920.
Good, M. F., Quakyi, I. A., Saul, A., Berzofsky, J. A., Carter, R. and Miller, L. H.: (1986) Human T cell clones reactive to the sexual stages of Plasmodium falciparum malaria — high frequency of gamete‑reactive T cells in peripheral blood from non‑exposed donors. J. Immunol. 138:306‑311.
Walliker, D., Quakyi, I. A., Wellems, T. E. McCutchan, T. F., Szarfman, A., London, W. T., Corcoran, L. M., Burkot, T. and Carter, R.: (1987) Genetic analysis of the human parasite Plasmodium falciparum. Science 236:1661‑166.
Quakyi, I. A., Carter, R., Rener, J., Kumar, N., Good, M. F. and Miller, L. H.: (1987). The 230 kDa gamete surface protein of Plasmodium falciparum is a target for transmission blocking antibodies: significance for vaccine development. J. Immunol. 139:4213‑4217.
Szarfman, A., Walliker, D., McBride, J., Lyon, J. A., Quakyi, I. A. and Carter, R.: (1988) Allelic forms of GP195, major blood stage antigen of P. falciparum, are expressed in liver stages. J. Exp. Med. 167:231‑236.
Good, M. F., Pombo, D., Quakyi, I. A., Riley, E. M., Houghten, R. A., Menon, A., Alling, D. W., Berzofsky, J. A. and Miller, L. H.: (1988). Human T cell recognition of the circumsporozoite protein of Plasmodium falciparum. Immunodominant T cell domains map to the polymorphic regions of the molecule. Proc. Natl. Acad. Sci. U.S.A. 85:1199‑1203.
Graves, P. M., Carter, R., Burkot, T., Quakyi, I. A. and Kumar, N.: (1988). Antibodies to Plasmodium falciparum gamete surface antigens in PNG sera. Parasitol. Immunol. 10:209‑218.
Szarfman, A., Lyon, J. A., Walliker, D., Quakyi, I. A., Howard, R. J., Sun, S., Ballou, W. R., Esser, K., London, W. T., Wirtz, R. A. and Carter, R.: (1988) Mature liver stages of P. falciparum share epitopes with proteins from sporozoites and asexual blood stages. Parasitol. Immunol. 10:339‑351.
Kumar, N., Syin, C., Carter, R., Quakyi, I. A. and Miller, L. H.: (1988) Plasmodium falciparum gene encoding a protein similar to the 78‑kDa rat glucose‑regulated stress protein. Proc. Natl. Acad. Sci. U.S.A. 85:6277‑6281.
Kaslow, D. C., Quakyi, I. A., Syin, C., Raum, M. G., Keister, D. B., Coligan, J. E., McCutchan, T. F. and Miller, L. H.: (1988) A vaccine candidate from the sexual stage of human malaria that contains EGF‑like domains. Nature 333:74‑76.
Kumar, S., Miller, L. H., Quakyi, I. A., Keister, D. B., Houghten, R. A., Maloy, W. L., Moss, B., Berzofsky, J. A. and Good, M. F.: (1988) Cytotoxtic T cells specific for the circumsporozoite protein of Plasmodium falciparum. Nature 334:258‑260.
Good, M. F., Miller, L. H., Kumar, S., Quakyi, I. A., Keister, D., Adams, J. H., Moss, B., Berzofsky, J. A. and Carter, R.: (1988) Limited immunological recognition of critical vaccine candidate antigens. Science 242:574‑577.
Dontfraid, F., Cochran, M. A., Pombo, D., Knell, J. D., Quakyi, I. A., Kumar, S., Houghten, R. A., Berzofsky, J. A., Miller, L. H. and Good, M. F.: (1988) Human and murine CD4 T‑cell epitopes map to the same region of sporozoite and circumsporozoite protein: limited immunogenicity of sporozoites and circumsporozoite protein. Mol. Biol. Med. 5:185‑196.
Quakyi, I. A., Matsumoto, Y., Carter, R., Udosanpetch, R., Berzins, K., Perlmann, P., Aikawa, M. and Miller, L. H.: (1989) Movement of a falciparum malarial protein through the erythrocyte cytoplasm to the erythrocyte membrane is associated with lysis of the erythroctye and release of gametes. Infect. Immun. 57:833‑839.
Carter, R., Graves, P. M., Quakyi, I. A. and Good, M. F.: (1989) Restricted or absent immune responses in human populations to Plasmodium falciparum gamete antigens which are targets of transmission‑blocking antibodies. J. Exp. Med. 169:135‑147.
Kaslow, D. C., Quakyi, I. A. and Keister, D. B.: (1989) Minimal variation in a vaccine candidate from the sexual stage of Plasmodium falciparum. Mol. Biochem. Parasitol. 32:101‑104.
De Groot, A. S., Johnson, A. H., Maloy, W. L., Quakyi, I. A., Riley, E. M., Menon, A., Banks, S. M., Berzofsky, J. A. and Good, M. F.: (1989) Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein. J. Immunol. 142:4000‑4005.
Quakyi, I. A., Otoo, L. N., Pombo, D., Sugars, L. Y., Menon, A., De Groot, A. S., Johnson, A., Alling, D., Miller, L. H. and Good, M. F.: (1989): Differential non‑responsiveness in humans to candidate Plasmodium falciparum vaccine antigens. Am. J. Trop. Med. Hyg. 41:125-134.
Good, M. F., Kumar, S. K., De Groot, A. S., Quakyi, I. A., Dontfraid, F., Cochran, M., Houghten, R. A., Berzofsky, J. A. and Miller, L. H. 1990. Immunogenicity of the circumsporozoite protein of Plasmodium falciparum. Bull. WHO. 68(suppl.):104‑108.
Carter, R., Graves, P. M., Keister, D. B. and Quakyi, I. A.: (1990) Properties of epitopes on Pfs 48/45, a target of transmission‑blocking antibodies on gametes of different isolates of Plasmodium falciparum. Parasite Immunol. 12:587-603.
Kaslow, D. C., Isaac, S., Quakyi, I. A., Gwadz, R. W., Moss, B., Keister, D. B.: (1991) Induction of Plasmodium falciparum transmission blocking antibodies by recombinant vaccinia virus. Science 252:1310‑1312.
Rodriguez-del Valle, R., Quakyi, I. A., Amuesi, J., Quaye, J. T., Nkrumah, F. K., Taylor, D. W.: (1991) Detection of antigens and antibodies in the urine of humans with Plasmodium falciparum malaria. J. Clin. Microbiol. 29:1236‑1242.
Barr, P. I., Green, K. M., Gibson, H. L., Barthurst, I. C., Quakyi, I. A., Kaslow, D. C. 1991. Recombinant Pfs25 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in experimental animals. J. Exp. Med. 174:1203‑1208.
Foo, A., Carter, R., Lambros, C., Graves, P. M., Quakyi, I. A., Targett, G. A. T., Ponnudurai, T.: (1991) Conserved and variant epitopes of target antigens of transmission-blocking antibodies in Plasmodium falciparum. Am. J. Trop. Med. Hyg. 44:623‑631.
Leke RGF, Ndansi R, Southerland N.J., Quakyi I.A., and Taylor.D.W.: (1992) Identification of anti-Plasmodiam falciparum antibodies in human breast milk. Scandinavian J. Immunol. 36(suppl.):17-22
Quakyi, I. A., Taylor, D. W., Johnson, A. H., Allotey, J.B., Berzofsky, J.A., Miller, L. H., Good, M. F.: (1992) Development of a Malaria T cell vaccine for Blood Stage Immunity. Scandinavian J. Immunol. 36(suppl.):9-16.
Bathurst, I.C., Gibson, H.L., Kansopon, J., Hahm, B.K, Green, K.M., Chang, S.P., Hui, G.S., Siddiqui, W.A., Inselburg, J., Millet, P., Quakyi, I.A., Kaslow, D.C., Barr, P.J. 1993. An experimental vaccine cocktail for Plasmodium falciparum malaria. Vaccine 11:449-456.
Quakyi I.A., Currier, J., Fell, A., Taylor, D.W., Roberts, T., England R.,Berzofsky, J. A., R., Miller, L.H., Good, M.F. 1994. Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins. Paucity of clones responsive to intact parasites. J. Immunol. 153:2082-2092.
Quakyi, I.A., Miller, L.H., Good, M.F., Ahlers J.D., Isaacs S.N., Nunberg J.H., Houghten, R.A., Keister, D.B., Colligan J.E., Moss, B., Alling, D., Berzofsky, J.A., and Kaslow, D.C.. 1995. Synthetic peptides fom Plasmodium falciparum sexual stage 25 kDa protein induce antibodies that react to native protein: The role of IL‑2 and conformational structure on immunogenicity of Pfs25. Peptide Research 8:335-344
Ellis JM, Leke, RFG, Quakyi I. A, Johnson AH, Hurley CK. 1997. Diversity is Demostrated in Class I HLA-A and HLA-B Alleles Present in Cameroon, Africa. Human Immunol. 55:116
Quakyi I.A., Ahlers J.D., 1999. CD4+ T helper cell responses-Lymphoproliferation. Part VII Immunological Techniques. In Malaria methods and protocols, Methods in Molecular Medicine. D.L Doolan. Humana Press, Totowa, NJ.
Johnson, A.H., Leke, R., Thuita Harun, L., Ngogang J., Ginsberg, C., Stowers, A., Saul A, and Quakyi, I.A. 2000. Interaction Between HLA-DQB1 and Age on the Production of Antibodies to Plasmodium falciparum Rhoptry-Associated Proteins. Infection and Immunity 68: 2231-2236.
Parra, M., Hui G., Johnson A.H., Roberts T., Quakyi I.A., Taylor D.W.2000. Characterization of T cell epitopes in Plasmodium falciparum major merozoite surface protein-1 (MSP-1). Infection and Immunity 68:2685-2691.
Ellis JM, Mack SJ, Leke,RFG, Quakyi I.A, Johnson AH, Hurley CK. 2000. Diversity is Demonstratedin Class I HLA-A and HLA-B Alleles Present in Cameroon, Africa. Description of HLA-A 03012, 2612, 3006, and HLA-B 1403, 1406 and 4703. Tissue Antigens 56:291-302.
Quakyi, I.A., Leke, R., Befidi-Mengue, R.,Tsafack M., Bomba-Nkolo, D., Manga, L, Tchinda, V.,Njeungue, E., Kouontchou, S., Fogako, J.,Nyonglema, P., Harun, L., Djokam, R., Sama, G., Eno, A., Megnekou R.,Metenou, S., Ndoutse L., Same-Ekobo, A., Alake, G., Meli, J., Ngu, J., Tietche, F., Lohoue, J., Mvondo., JL., Wansi, E., Leke, R., Folefack, A., Bigoga J., Bomba-Nkolo, C., Titanji, V., Walker-Abbey, A. Hickey M., Johnson, A.H., Taylor, D.W. 2000. The Epidemiology of Plasmodium falciparum Malaria in Two Cameroonian Villages: Simbok and Etoa. Am J Trop Med Hyg 63:222-30.
Ellis JM, Hoyer RJ, Costello CN, Mshana RN, Quakyi I.A, Mshana MN, Diaby B, Traore T, Johnson AH, Katovich Hurley C. 2001. HLA-B Allele Frequencies in Cote diIvoire Defined by Direct DNA Sequencing: Identification of HLA-B 1405, B 4410 and B 5302. Tissue Antigens 57:339-4
J. R. Ryan, K. Davé, K. M. Collins,L. Hochberg, J. Sattabongkot, R. F. Dunton, M. J. Bangs, C. M. Mbogo, R. D. Cooper, G. B. Schoeler, Y. Rubio, M. Magris, L. I. Romero, N. Padilla, I. A. Quakyi, J. Bigoga , R. G. Leke, C. F. Curtis, B. Evans, M. Walsey, P. Patterson, R. A. Wirtz, and A. S. T. Chan. 2002. Extensive Multiple Test Center Evaluation of the VecTest Malaria Antigen Panel Assay. Med. Vet. Entomol. 16:321-7
Kouontchou S, Quakyi I, A, Befidi R, Tchinda, Tamo R, Nyonglema P.G, Fogako J, Leke RG.F. 2002. Prevalence of multiple concomitant intestinal parasitic infections in Simbok, a malaria endemic village in Cameroon. The Journal of the Cameroon Academy of Sciences Vol. 2 Supplement.
Kouontchou S, TamaD.R.R, TchindaV. Tietche M.H.F, Fogako, J, Sama G, J Meli, Kago I ,Ngu J, Alake G. Quakyi I, A, Leke R..2002. A longitudinal study of the role of T cell subset, Th1/Th2 cytokines and antiplasmodial antibodies in uncomplicated malaria in a village population chronically exposed to Plasmodium falciparum malaria. The Journal of the Cameroon Academy of Sciences Vol. 2 Supplement
Johnson AH, Leke RFG, Mendell NR, Shon D, Bomba-Nkolo D, Tchinda V, Kouontchou S, Thuita Harun L, van der Wel AM, Thomas A, Stowers A, Saul A, Taylor DW, Quakyi IA. 2004. Human leukocyte antigen class II alleles influence levels of antibodies to the Plasmodium falciparum asexual-stage apical membrane antigen 1 but not to merozoite surface antigen 2 and merozoite surface protein 1. Infection and Immunity. 72: 2762-2771.
Tabi T-E, Befidi-Mengue R, Nutman TB, Horton J, Folefack A, Pensia E, Fualem R, Fogako J, Gwanmesia P, Quakyi I, Leke R. 2004. Human Loiasis in a Cameroonian village: A double-Blind, Placebo-controlled crossover clinical trial of a 3 day Albendazole regimen. Am J Trop Med Hyg. 71:211-5.
Udeinya, I.J.; Brown, N.; Shu, E.N.; Udeinya, F.I.; Quakyi, I. 2006. Fractions of an antimalarial neem-leaf extract have activities superior to chloroquine, and are gametocytocidal Annals of Tropical Medicine and Parasitology, 100: 17-22
Howard CT, McKakpo US, Quakyi IA, Bosompem KM, Addison EA, Sun K, Sullivan D, Semba RD. 2007. Relationship of hepcidin with parasitemia and anemia among patients with uncomplicated Plasmodium falciparum malaria in Ghana. Am J Trop Med Hyg.77: 623-6.
Udeinya JI, Shu EN, Quakyi I, Ajayi FO. 2008 An antimalarial neem leaf extract has both schizonticidal and gametocytocidal activities. American Journal of Therapeutics.15:108-10
Frempong, K.K., Quakyi, I., Ben-Mahmoud, S.K., Owusu, I.O., Appawu, M.A. and Boakye, D., 2008, December. biochemical and knockdown resistance of anopheles gambiae to permethrin and deltamethrin (pyrethroids) at kpone on sea in the greater accra region of ghana. in american journal of tropical medicine and hygiene (vol. 79, no. 6, pp. 70-70). 8000 westpark dr, ste 130, mclean, va 22101 usa: amer soc trop med & hygiene.
Laar AK., Ampofo W., Tuakli JM., Wonodi C., Asante RK., and Quakyi IA. 2009.Factors associated with suboptimal intake of some important nutrients among HIV-positive pregnant adolescents from two Ghanaian districts. Journal of the Ghana Science Association. 11: 25-39.
Laar AK., Ampofo W., Tuakli JM., and Quakyi IA.2009. Infant feeding choices and experiences of HIV-positive mothers from two Ghanaian districts.Journal AIDS and HIV Research. 1: 23-33.
Oni G., Fatusi A., Tsui A., Enquselassie F., Ojengbede O., Agbenyega T., Ojofeitumi E., Taulo F., Quakyi I. 2010. Strengthening public-health education in population and reproductive health through an innovative academic partnership in Africa: The Gates partners experience. iFirst Article: Global Public health journal. 1-17.
Quakyi I.A., Tsui A. 2010. Building Leadership and Capacity in Health Research in Ghana. Proceedings of XII ICOPA. Melbourne Australia. Medimont S. R. I.Publishers
Mahajan .B, Zheng H., Pham P. T., Sedegah M. Y., Majam V. F., Akolkar N., Rios M.,. Ankrah I, Madjitey P., Amoah G., Addison E., Quakyi I. A., Kumar S. Polymerase chain reaction based tests for pan-species and species-specific detection of human Plasmodium parasites. Transfusion, 2011-0626.R
Mahajan B., Majam V. F.,Moitra P., Kozakai Y., Pham P. T., Zheng H., Lanar D. E., David L Narum D. L., Quakyi I. A., Kumar S. Multiplex multi-antigen, multi-species, microsphere- based ELISA to detect antibodies to three human Plasmodium speciesMalar J. 2012; 11(Suppl 1): P119. Published online 2012 October 15. doi: 10.1186/1475-2875- 11- S1-P119.
Tchouassi, D.P, Quakyi, I.A, Addison E.A, Bosompem K.M, Wilson M.D, Appawu M.A, Brown, C. A & Boakye, D. A (2012). Characterization of malaria transmission by vector populations for improved interventions during the dry season in the Kpone-on-Sea area of coastal Ghana. Parasite Vectors 2012 Sept 26; 5 (1):212.
Laar, A. K., Grant, F. E., Addo, Y., Soyiri, I., Nkansah, B., Abugri, J., Quakyi, I. A. (2013). Predictors of fetal anemia and cord blood malaria parasitemia among newborns of HIV-positive mothers. BMC Res Notes, 6, 350. doi: 10.1186/1756-0500-6-350
Stephens, J. K., Ofori, M. F., Quakyi, I. A., Wilson, M. L., & Akanmori, B. D. (2014). Prevalence ofperipheral blood parasitaemia, anaemia and low birthweight among pregnant women in a suburban area in coastal Ghana. Pan Afr Med J, 17 Suppl 1, 3. doi: 10.11694/pamj.supp.2014.17.1.3541
Babakhanyan, A., Leke, R. G., Salanti, A., Bobbili, N., Gwanmesia, P., Leke, Quakyi I. A., Chen J. J., R.J., Taylor, D. W. (2014). The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site. PLoS One, 9(2), e88173. doi: 10.1371/journal.pone.0088173
Laar A, Fiaveh D, Laar M, Boatemaa S, Abugri J, El-Adas A, Amenyah R, Atuahene K, Adjei A A, Quakyi I. (2014), Profiles of HIV-Affected households in Ghana, Health, 6, 2004-2013.http://www.scirp.org/journal/health
Babakhanyan, A., Leke, R.G., Salanti, A., Bobbili, N., Gwanmesia, P., Leke, R.J., Quakyi, I.A., Chen, J.J. and Taylor, D.W., 2014. The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site. PloS one, 9(2), p.e88173.
Laar AK , El-Adas A, Amenyah RN, Atuahene K, Asare E, Tenkorang EY, Laar M, Adjei AA and Quakyi I (2015) Food and nutrition assistance to HIV-infected and affected populations in Ghana: a situational analysis and stakeholder views. African Geographical Review, 34:1, 69-82, DOI: 10.1080/19376812.2014.964739
Laar AK, Manu A, Laar M, El-Adas A, Amenyah R, Atuahene K, Quarshie D Adjei AA Quakyi I (2015). Coping Strategies of HIV-affected Households in Ghana. BMC Public Health 2015, 15:166. doi:10.1186/s12889-015-1418-x
Fodjo, B.A., Atemnkeng, N., Esemu, L., Yuosembom, E.K., Quakyi, I.A., Tchinda, V.H., Smith, J., Salanti, A., Bigoga, J., Taylor, D.W. and Leke, R.G., 2016. Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers. Malaria Journal, 15(1), p.532.
Alnasser, Y., Ferradas, C., Clark, T., Calderon, M., Gurbillon, A., Gamboa, D., McKakpo, U.S., Quakyi, I.A., Bosompem, K.M., Sullivan, D.J. and Vinetz, J.M., 2016. Colorimetric Detection of Plasmodium vivax in Urine Using MSP10 Oligonucleotides and Gold Nanoparticles. PLoS neglected tropical diseases, 10(10), p.e0005029.
Markakpo, U.S., Bosompem, K.M., Dzodzomenyo, M., Danso‐Appiah, A., Essuman, E.E., Anyan, W.K., Suzuki, M., Stephens, J.K., Anim‐Baidoo, I., Asmah, R.H. and Ofori, M.F., Quakyi, IA (2016). Minimising invasiveness in diagnostics: developing a rapid urine‐based monoclonal antibody dipstick test for malaria. Tropical Medicine & International Health, 21(10), pp.1263-1271.
Adjei, A.A., Winch, P., Laar, A., Sullivan, D.J., Sakyi, K.S., Stephens, J.K., Adjei, G.O., Boateng, I.A., Aubyn, V.N.A., Kubio, C. and Tuakli, J., Quakyi, IA (2016). Insights into the Affordable Medicines Facility-malaria in Ghana: the role of caregivers and licensed chemical sellers in four regions. Malaria journal, 15(1), p.1.
Taylor, D. W., Bobbili, N., Khadka, V. S., Quakyi, I. A., & Leke, R. G. (2017). Individuals living in a malaria-endemic area of Cameroon do not have an acquired antibody response to Plasmodium falciparum histidine-rich protein 2. Malaria Journal, 16(1), 58.
Essuman, E., Grabias, B., Verma, N., Chorazeczewski, J.K., Tripathi, A.K., Mlambo, G., Addison, E.A., Amoah, A.G., Quakyi, I. A, Oakley, M.S. and Kumar, S., 2017. A Novel Gametocyte Biomarker for Superior Molecular Detection of the Plasmodium falciparum Infectious Reservoirs. The Journal of infectious diseases, 216(10), pp.1264-1272.
Stephens, J.K., Kyei-Baafour, E., Dickson, E.K., Ofori, J.K., Ofori, M.F., Wilson, M.L., Quakyi, I.A. and Akanmori, B.D., 2017. Effect of IPTp on Plasmodium falciparum antibody levels among pregnant women and their babies in a sub-urban coastal area in Ghana. Malaria journal, 16(1), p.224
Quakyi, I.A., Adjei, G.O., Sullivan, D.J., Stephens, J.K., Laar, A., Aubyn, V.N.A., Owusu, R., Sakyi, K.S., Coleman, N., Krampa, F.D., Vanotoo, L., Tuakli J., Bortei B. B., Essuman E., Sorvor F., Boateng I. A., Bart-Plange C., Addison E A., Winch P., and Adjei A. A. 2017. Targeted community based interventions improved malaria management competencies in rural Ghana. Global health research and policy, 2(1), p.29
Quakyi, I.A., Adjei, G.O., Sullivan, D.J., Stephens, J.K., Laar, A., Aubyn, V.N.A., Owusu, R., Sakyi, K.S., Coleman, N., Krampa, F.D., Vanotoo, L., Tuakli J., Bortei B. B., Essuman E., Sorvor F., Boateng I. A., Bart-Plange C., Addison E A., Winch P., and Adjei A. A. 2018. Diagnostic capacity, and predictive values of rapid diagnostic tests for accurate diagnosis of Plasmodium falciparum in febrile children in Asante-Akim, Ghana. Malaria journal 17.1: 468
Lamptey, H., Ofori, M.F., Kusi, K.A., Adu, B., Owusu-Yeboa, E., Kyei-Baafour, E., Arku, A.T., Bosomprah, S., Alifrangis, M. and Quakyi, I.A., 2018. The prevalence of submicroscopic Plasmodium falciparum gametocyte carriage and multiplicity of infection in children, pregnant women and adults in a low malaria transmission area in Southern Ghana. Malaria journal, 17(1), p.331
Lamptey, H., Ofori, M.F., Adu, B., Kusi, K.A., Dickson, E.K., Quakyi, I. and Alifrangis, M., 2019. Association between alpha-thalassaemia trait, Plasmodium falciparum asexual parasites and gametocyte carriage in a malaria endemic area in Southern Ghana. BMC research notes, 12(1), p.134.
Essuman, E., Grabias, B., Verma, N., Chorazeczewski, J.K., Tripathi, A.K., Mlambo, G., Addison, E.A., Amoah, A.G., Quakyi, I., Oakley, M.S. and Kumar, S., 2017. A novel gametocyte biomarker for superior molecular detection of the Plasmodium falciparum infectious reservoirs. The Journal of infectious diseases, 216(10), pp.1264-1272.
Grabias, B., Essuman, E., Quakyi, I.A. and Kumar, S., 2019. Sensitive real-time PCR detection of Plasmodium falciparum parasites in whole blood by erythrocyte membrane protein 1 gene amplification. Malaria journal, 18(1), p.116.
Quakyi, I., Tornyigah, B., Houze, P., Kusi, K.A., Coleman, N., Escriou, G., Laar, A., Cot, M., Fobil, J., Asare, G.Q. and Deloron, P., 2019. High uptake of Intermittent Preventive Treatment of malaria in pregnancy is associated with improved birth weight among pregnant women in Ghana. Scientific Reports, 9(1), pp.1-8.
Tornyigah, B., Coppée, R., Houze, P., Kusi, K.A., Adu, B., Quakyi, I., Coleman, N., Mama, A., Deloron, P., Anang, A.K. and Clain, J., 2020. Effect of Drug Pressure on Promoting the Emergence of Antimalarial-Resistant Parasites among Pregnant Women in Ghana. Antimicrobial Agents and Chemotherapy, 64(6).
Ayettey S.A., Quakyi I.A, Ayettey-Anie H.NG., Sagoe K.W., Ayettey-Adamafio M.NB, Newman-Nartey M., Ayettey Brew R. NA, Nartey N.O., Amoah A.GB., Konotey-Ahulu FID. A Case for Hydrogen Peroxide Mouthwash and Gargle to limit SARS-CoV-2 Infection. BMJ July 2 2020 Rapid Response to COVID-19: What treatments are being investigated? BMJ 2020; 368: m1252 https://www.bmj.com/content/370/bmj.m1252/rr-27
Konotey-Ahulu FID, Quakyi I.A., Ayettey-Anie H.NG., Sagoe K.W., Ayettey-Adamafio M.N., Newman-Nartey M,, Ayettey Brew R.NA., Nartey N.O., Amoah A.GB, Ayettey A.S. Efficient Protection of Contacts is Simpler than Imagined http://orthomolecular.org/resources/omns/v16n46.shtml September 3 2020.
Acquah, A. A., D'Souza, C., Martin, B., Arko-Mensah, J., Qaukyi, I. A., Basu, N., Robins, T. G., Fobil, J. N. (2021). Work-Related Exposures and Musculoskeletal Disorder Symptoms Among Informal E-Waste Recyclers at Agbogbloshie, Ghana. In: Black N.L., Neumann W.P., Noy I. (eds) Proceedings of the 21st Congress of the International Ergonomics Association (IEA 2021). IEA 2021. Lecture Notes in Networks and Systems, vol 222. Springer, Cham. https://doi.org/10.1007/978-3-030-74611-7_93
Acquah, A.A., D’Souza, C., Martin, B. J., Arko-Mensah, J., Dwomoh, D., Nti, A.A. A., Kwarteng, L., Takyi, S. A., Basu, N., Quakyi, I.A., Robins, T.G., Fobil, J.N. Musculoskeletal Disorder Symptoms among Workers at an Informal Electronic-Waste Recycling Site in Agbogbloshie, Ghana. Int. J. Environ. Res. Public Health 2021, 18, 2055. https://doi.org/10.3390/ijerph18042055
Acquah, A.A., D'souza, C., Martin, B., Arko-Mensah, J., Botwe, P.K., Tettey, P., Dwomoh, D., Nti, A.A., Kwarteng, L., Takyi, S., Quakyi, I.A., Robins, T.G., Fobil, J.N. (2020). A Preliminary Assessment of Physical Work Exposures Among Electronic Waste Workers at Agbogbloshie, Accra Ghana. International Journal of Industrial Ergonomics 82 (2021) 103096. https://doi.org/10.1016/j.ergon.2021.103096
Acquah, A.A., D’Souza, C., Martin, B., Arko-Mensah, J., Nti, A.A., Kwarteng, L., Takyi, A., Botwe, P.K., Tettey, P., Dwomoh, D., Quakyi, I.A., Robins, T.G., Fobil, J.N. (2020). Development of an observation-based tool for ergonomic exposure assessment in informal electronic waste recycling and other unregulated non-repetitive work. Proceedings of the Human Factors and Ergonomics Society Annual Meeting. 2020;64(1):905-909. https://doi.org/10.1177/1071181320641216
Acquah, A.A., D’Souza, C., Martin, B., Arko-Mensah, J., Nti, A.A., Kwarteng, L., Takyi, S., Quakyi, I.A., Robins, T.G., Fobil, J.N. (2019). Processes and challenges associated with informal electronic waste recycling at Agbogbloshie, a suburb of Accra, Ghana. Proceedings of the Human Factors and Ergonomics Society Annual Meeting, 63(1), 938–942. https://doi.org/10.1177/1071181319631219
Acquah, A.A., D’souza, C., Martin, B.J., Arko-Mensah, J., Basu, N., Quakyi, I.A., Robins, T.G., Fobil, J.N. (2021). Comparison of ergonomic risk factors and work-related musculoskeletal disorders among dismantler and burners of electronic waste in Agbogbloshie, Accra Ghana. Proceedings of the Human Factors and Ergonomics Society Annual Meeting (Accepted for publication)
Tripathi, A.K., Oakley, M.S., Verma, N., Mlambo, G., Zheng, H., Meredith, S.M., Essuman, E., Puri, A., Skelton, R.A., Takeda, K. Majam, V., Quakyi I.A., Locke E., Morin M., Miura K., Long C.A., Kumar S. 2021. Plasmodium falciparum Pf77 and male development gene 1 as vaccine antigens that induce potent transmission-reducing antibodies. Science Translational Medicine, 13(597).
Amoah GB, Quakyi IA, Sagoe KW, Ayettey-Anie HNG, Ayettey-Adamafio MNB, Ayettey Brew RNA, Newman-Nartey M, Nartey NO, Brightson KTC, Kessie G, Ayettey AS, Konotey-Ahulu FID.J Hosp Infect. 2021 Sep 3:S0195-6701(21)00311-X. doi: 10.1016/j.jhin.2021.08.024.
Acquah, A. A., D’Souza, C., Martin, B. J., Arko-Mensah, J., Basu, N., Quakyi, I. A., Robins, T. G., & Fobil, J. N. (2021). Comparison of ergonomic risk factors and work-related musculoskeletal disorders among dismantler and burners of electronic waste in Agbogbloshie, Accra Ghana. Proceedings of the Human Factors and Ergonomics Society Annual Meeting, 65(1), 715–719. https://doi.org/10.1177/1071181321651256
Ongoing Projects
Title | Role on the Project | Duration of the Project | Funder |
COCOA AS AN ENCHANCER IN THE MANAGEMENT OF SOME LIFE-THREATENING INFECTIOUS AND METABOLIC DISEASES COLLABORATIVE RESEARCH: GHANA COCOA BOARD (COCOBOD) AND GHANA ACADEMY OF ARTS AND SCIENCES | CO-Investigator | 2021 -2022 | GHANA COCOA BOARD (COCOBOD) |
Completed Projects
Title | Role on the Project | Duration of the Project | Funder | |
Intermittent Preventive Treatment of Malaria in Pregnancy. Assessing the New Implementation Strategy in Ghana. | Principal Investigator | 2015 - 2017
| FEI Initiative. Mission No. 14SANIN163 | |
Improving Correct Diagnosis and Treatment of Malaria in Rural Ghana. | Co-Principal Investigator
| 2010-2014 | Grant No. CHAI/2/2011 | |
Development of Distance Learning Capacity and Materials.
| Principal Investigator | 2006/2007-2010 | National Centre for Tertiary Education No.CHSR/4/11/2006 | |
Development of Distance Learning Capacity and Materials.
| Principal Investigator | 2006/2007-2010 | National Centre for Tertiary Education No.CHSR/4/11/2006
| |
HIV/AIDS Interactive Training, Education and Development Centre
| Principal Investigator | 2006-2008 | National Centre for Tertiary EducationNo. CHSR/3/004/2005
| |
Reduction of HIV Transmission and Severity in Mother-To-Child Transmission.
| Principal Investigator | 2005-2007 | National Centre for Tertiary Education No CHS/R/01/2005 | |
Development of a Reference Guide “Status Disclosure and Partner Notification” For Human Immunodeficiency Virus (HIV) Voluntary Counseling and Testing (VCT) Trainers/Counselors.
| Principal Investigator | 2005 – 2006 | National Centre for Tertiary Education No. CHSS/002/2004
| |
A Pilot Study of Youth and On Line Health Seeking in Accra, Ghana.
| Principal Investigator | 2005 | Johns Hopkins Bloomberg School of Public Health, GatesInstitute for Population and Reproductive Health No. 979-2020
| |
Construction of a New Wing to the School of Public Health.
| Principal Investigator | 2005 | Johns Hopkins Bloomberg School of Public Health, Gates Institute for Population and Reproductive Health No. 979-2020 | |
Creation of The Population Family and Reproductive Department
| Principal Investigator | 2003-2008 | Johns Hopkins Bloomberg School of Public Health, Gates Institute for Population and Reproductive Health No. 9792020/2378 | |
A Multidisciplinary Case-Control Study of Malaria Pathogenesis and Immunity in Ghana, West Africa.
| Principal Investigator | 2003-2008 | MIM/TDR/WHO No. A30033
| |
The effect of Th2-Bias on Malarial Immunity in Cameroon.
| CO-Investigator | 1998-2003 | National Institutes of Health NIAID N01-AI43888
| |
Immune Disregulation in Malaria and Concomitant Measles
| Principal Investigator | 1998-2001 | National Institutes of Health/Fogarty International Center (Fogarty International Research Collaboration Award) FIRCA# 1 R03TW00951-01 | |
Application of data on HLA System to the Development of Vaccines and Influence of HLA and other Genes on Responses to vaccines.
| CO-Investigator | 1994-1999 | National Institutes of Health-NIAID# N01 -AI-45242
| |
Acquisition of Immunity to malaria in the Cameroon in Children and Adults.
| Principal Investigator | 1994-1999 | National Institutes of Health/NIAID (International Collaboration for Infectious Disease Research) # 1 UO1 AI35839 - 01
| |
MHC Genes and Major Malaria Asexual‑Stage T Cell Epitopes (Identification Conserved T cell epitopes in Plasmodium falciparum asexual-stage antigens).
| CO- Principal Investigator | 1990-1994 | United States Agency for International Development # DPE-5979-A-00-0034-00 | |
Immunoradiometric Assays Using Monoclonal Antibodies for the Detection of Circulating or Urinary Antigens in Patients with Filariasis, Malaria, or Schistosomiasis [part of a coordinated program on nuclear techniques for the detection of parasite antigens in body fluids]
| Principal Investigator | 1982-1983 | International Atomic Energy Agency # 3233/RB | |
Application and Development of Immunological Methods to Epidemiological Studies in Ghana, University of Ghana Medical School
| Principal Investigator | 1980-1983 | World Health Organization/Tropical Disease Research, Re-entry # 10 800484 |